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polyclonal antibody against chop  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology polyclonal antibody against chop
    Polyclonal Antibody Against Chop, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 653 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Representative light microscopic screen images of liver tissue sections incubated with <t>CHOP</t> primary antibody. ( A ) (×20). Control group: In the liver tissue sections from the control group, hepatocytes with a normal structure (arrow) were observed to be CHOP-negative (CHOP positivity score: 0(0-0)). ( B ) (×20). I/R group: In the intralobular areas, primarily in Zone 1, hepatocytes showing intense CHOP positivity (spiral arrow) are observed (CHOP positivity score: 2(1-2)). ( C ) (×20). I/R+TMZ group: A decrease in hepatocytes showing CHOP positivity was observed in the perinobular areas, particularly in the intralobular regions (CHOP positivity score: 1(0-1)). ( D ) (×20). I/R+DEX group: A decrease in hepatocytes showing intense immunopositivity in the intralobular and perilobular areas was observed, with a widespread presence of CHOP-negative hepatocytes (arrow, CHOP positivity score: 0.5 (0-1)).
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    Representative light microscopic screen images of liver tissue sections incubated with <t>CHOP</t> primary antibody. ( A ) (×20). Control group: In the liver tissue sections from the control group, hepatocytes with a normal structure (arrow) were observed to be CHOP-negative (CHOP positivity score: 0(0-0)). ( B ) (×20). I/R group: In the intralobular areas, primarily in Zone 1, hepatocytes showing intense CHOP positivity (spiral arrow) are observed (CHOP positivity score: 2(1-2)). ( C ) (×20). I/R+TMZ group: A decrease in hepatocytes showing CHOP positivity was observed in the perinobular areas, particularly in the intralobular regions (CHOP positivity score: 1(0-1)). ( D ) (×20). I/R+DEX group: A decrease in hepatocytes showing intense immunopositivity in the intralobular and perilobular areas was observed, with a widespread presence of CHOP-negative hepatocytes (arrow, CHOP positivity score: 0.5 (0-1)).
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    Image Search Results


    Representative light microscopic screen images of liver tissue sections incubated with CHOP primary antibody. ( A ) (×20). Control group: In the liver tissue sections from the control group, hepatocytes with a normal structure (arrow) were observed to be CHOP-negative (CHOP positivity score: 0(0-0)). ( B ) (×20). I/R group: In the intralobular areas, primarily in Zone 1, hepatocytes showing intense CHOP positivity (spiral arrow) are observed (CHOP positivity score: 2(1-2)). ( C ) (×20). I/R+TMZ group: A decrease in hepatocytes showing CHOP positivity was observed in the perinobular areas, particularly in the intralobular regions (CHOP positivity score: 1(0-1)). ( D ) (×20). I/R+DEX group: A decrease in hepatocytes showing intense immunopositivity in the intralobular and perilobular areas was observed, with a widespread presence of CHOP-negative hepatocytes (arrow, CHOP positivity score: 0.5 (0-1)).

    Journal: Biomedicines

    Article Title: Protective Effects of Trimetazidine and Dexmedetomidine on Liver Injury in a Mesenteric Artery Ischemia–Reperfusion Rat Model via Endoplasmic Reticulum Stress

    doi: 10.3390/biomedicines12102299

    Figure Lengend Snippet: Representative light microscopic screen images of liver tissue sections incubated with CHOP primary antibody. ( A ) (×20). Control group: In the liver tissue sections from the control group, hepatocytes with a normal structure (arrow) were observed to be CHOP-negative (CHOP positivity score: 0(0-0)). ( B ) (×20). I/R group: In the intralobular areas, primarily in Zone 1, hepatocytes showing intense CHOP positivity (spiral arrow) are observed (CHOP positivity score: 2(1-2)). ( C ) (×20). I/R+TMZ group: A decrease in hepatocytes showing CHOP positivity was observed in the perinobular areas, particularly in the intralobular regions (CHOP positivity score: 1(0-1)). ( D ) (×20). I/R+DEX group: A decrease in hepatocytes showing intense immunopositivity in the intralobular and perilobular areas was observed, with a widespread presence of CHOP-negative hepatocytes (arrow, CHOP positivity score: 0.5 (0-1)).

    Article Snippet: The liver tissue slices were analyzed via immunohistochemistry labeling with primary antibodies against CHOP (E-AB-70087, 1/300, Elabscience, Houston, TX, USA), GPR78 (SC-13539, 1/350, Santa Cruz Biotechnology Inc. Dallas, TX, USA), 8-hydroxy-2′-deoxyguanosine (8-OHdG) (Santa Cruz, SC-66036, 1/200, Santa Cruz Biotechnology Inc., Dallas, TX, USA), cleaved caspase-3 (Abcam, ab4051, 1/100), anti-Bax ab32503, 1/200, (Abcam, Cambridge, UK), and anti-Bcl-2 (Abcam, ab32124, 1/200).

    Techniques: Incubation, Control